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Itaconate alleviates anesthesia/surgical procedures-induced cognitive impairment by activating a Nrf2-dependent anti-neuroinflammation and neurogenesis through gut-Mind axis Xiangyi KongPlasma and brains have been gathered at the end of the study. Baseline groups of naïve (untreated) rTg4510 mice ended up also sacrificed at 8 or 12 weeks of age (